SCHEMBL5602318

SCHEMBL5602318

Cc1ccccc1-c1cccc2c1C1=C(CCC1)[N]2

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
FLT1 P17948 1/20 0.31
CDK8 P49336 1/20 0.31
CDK9 P50750 1/20 0.31
LIMK1 P53667 1/20 0.31
ROCK1 Q13464 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
NISCH Q9Y2I1 1/20 0.31
BRD4 O60885 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604115 0.85 ACHE (0.33)
SCHEMBL5603961 0.81 CYP2A6 (0.33)
SCHEMBL5604144 0.81 PTGS2 (0.36) NPC1RAB9ASMN1; SMN2
SCHEMBL5612683 0.72 GABRA1 (0.33)
SCHEMBL5603752 0.72
SCHEMBL5604054 0.72 ADORA3 (0.31)
SCHEMBL693484 0.71 ACHE (0.33)
SCHEMBL5601378 0.71 ADORA3 (0.31)
SCHEMBL5602017 0.71 ADORA3 (0.31)
SCHEMBL5601566 0.71 ADORA3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed