SCHEMBL5602984

SCHEMBL5602984

CC1=C(Cc2ccccc2)[N]c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TAAR1 Q96RJ0 1/20 0.34
S100A4 P26447 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TBXAS1 P24557 1/20 0.33
LTA4H P09960 1/20 0.33
ALPL P05186 1/20 0.33
MAOB P27338 1/20 0.33
GAA P10253 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601003 0.73 HSD11B1 (0.35) TDP1ALDH1A1TSHRPTPN1
SCHEMBL5601435 0.70 KCNH2 (0.41) NR1H2NR1H3PTPN1
SCHEMBL5600379 0.70 KCNH2 (0.41) NR1H2NR1H3PTPN1
SCHEMBL5602347 0.70 KCNH2 (0.41) NR1H2NR1H3PTPN1
SCHEMBL1091995 0.69 HSD11B1 (0.34) NPC1RAB9ASMN1; SMN2S100A4ALDH1A1
SCHEMBL5603469 0.68 IDH1 (0.38) CALM1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL5603742 0.66 HTR2A (0.39) CALM1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL5601414 0.65 CALM1 (0.42) CALM1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL5599623 0.62 S1PR1 (0.31) ALDH1A1PTPN1
SCHEMBL3690828 0.62 CALM1 (0.55) CALM1TAAR1ALDH1A1TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed