⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513337 | 0.73 | CA3 (0.58) | — | |
| SCHEMBL673609 | 0.73 | APP (0.74) | — | |
| SCHEMBL14400750 | 0.73 | APP (0.74) | — | |
| Hydroquinone SCHEMBL18095025 | 0.71 | HSD17B10 (0.80) | — | |
| Hydroquinone SCHEMBL460669 | 0.71 | ALOX15 (1.00) | — | |
| Hydroquinone SCHEMBL11511669 | 0.71 | ALOX15 (1.00) | — | |
| Hydroquinone SCHEMBL15516 | 0.71 | — | — | |
| 4-Cyanophenol SCHEMBL4820911 | 0.69 | CA2 (0.84) | — | |
| SCHEMBL6443716 | 0.69 | APP (0.43) | — | |
| SCHEMBL4007018 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634705-A | Heat and sound insulation blanket for vehicle and preparation method thereof | 张影 | 2022-06-17 | — | — | CN | claimed |
| EP-1009738-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2004-05-19 | — | — | EP | claimed |
| US-6541503-B2 | Preventing chemotherapy induced alopecia. | SMITHKLINE BEECHAM CORPORATION | 2003-04-01 | — | — | US | claimed |
| US-20030004351-A1 | Substituted oxindole derivatives as protein tyrosine kinase and as protein serine/threonine kinase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-01-02 | — | — | US | claimed |
| CN-114634705-A | Heat and sound insulation blanket for vehicle and preparation method thereof | 张影 | 2022-06-17 | — | — | CN | disclosed |
| US-10274500-B2 | Characterization of subvisible particles using a particle analyzer | BAXALTA INCORPORATED (US) | 2019-04-30 | — | — | US | disclosed |
| US-9645128-B2 | Substituted imidazo[1,2-A]pyrazines for measuring a transcription activity | JNC CORPORATION (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20170121755-A1 | COELENTERAZINE ANALOGS | JNC CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-9567623-B2 | Coelenterazine analogs | JNC CORPORATION (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9346767-B2 | Substituted pyrazines and a process for producing the same | JNC CORPORATION (JP) | 2016-05-24 | — | — | US | disclosed |
| US-20150344936-A1 | COELENTERAZINE ANALOGS AND MANUFACTURING METHOD THEREOF | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-12-03 | — | — | US | disclosed |
| US-9151739-B2 | Coelenterazine analogs and manufacturing method thereof | JNC CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| US-8642281-B2 | Coelenterazine analogues and coelenteramide analogues | JNC CORPORATION (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20140024058-A1 | COELENTERAZINE ANALOGS AND MANUFACTURING METHOD THEREOF | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2014-01-23 | — | — | US | disclosed |
| US-8546568-B2 | Coelenterazine analogs and manufacturing method thereof | JNC CORPORATION (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20130177933-A1 | Characterization of Subvisible Particles Using a Particle Analyzer | BAXTER HEALTHCARE SA (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20120232272-A1 | PROCESS FOR PRODUCING v-COELENTERAZINE COMPOUNDS | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120035070-A1 | COELENTERAZINE ANALOGS AND MANUFACTURING METHOD THEREOF | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20110244481-A1 | COELENTERAZINE ANALOGUES AND COELENTERAMIDE ANALOGUES | JNC CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-1009738-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AS PROTEIN TYROSINE KINASE AND AS PROTEIN SERINE/THREONINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2004-05-19 | — | — | EP | disclosed |