Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5601369 | 0.87 | CNR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5601613 | 0.83 | CA1 (0.37) | ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5601852 | 0.83 | CA1 (0.38) | ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5602820 | 0.76 | PRKD3 (0.37) | — | |
| Hydrochloric Acid SCHEMBL5599752 | 0.76 | — | — | |
| SCHEMBL5603549 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4EATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL5602738 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL29612346 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14557135 | 0.67 | ALDH1A1 (0.55) | ALDH1A1KDM4EATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL8426993 | 0.67 | CHRNB2 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |