Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7638525 | 0.92 | EDNRB (0.31) | CHRNB2CHRNA4EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL5689682 | 0.83 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3682026 | 0.82 | LMNA (0.33) | ALDH1A1HSD17B10HPGDEDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL29612346 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPK1EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL3683429 | 0.78 | NPC1 (0.36) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4089006 | 0.77 | CHRNB2 (0.35) | CHRNB2CHRNA4BRD4PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL3685419 | 0.77 | CHRNB2 (0.35) | CHRNB2CHRNA4BRD4PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL4088340 | 0.77 | CHRNB2 (0.35) | CHRNB2CHRNA4BRD4PARP10PARP11 | |
| Hydrochloric Acid SCHEMBL7623229 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27488712 | 0.76 | CHRNB2 (0.34) | CHRNB2CHRNA4ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118223194-A | Soft and durable nonwoven web | 金伯利-克拉克环球有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116728919-A | Laterally extensible nonwoven composites | 金伯利-克拉克环球有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-105722485-B | Absorbent article comprising a soft and durable backsheet | 金伯利-克拉克环球有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-5962359-A | Metallocene compound and its use as catalyst component | TARGOR GMBH (DE) | 1999-10-05 | — | — | US | disclosed |