Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5872671 | 0.80 | ALDH1A1 (0.35) | CYP1A2CYP2C19ALDH1A1CYP2A6TSHR | |
| Hydrochloric Acid SCHEMBL965025 | 0.76 | KDM4E (0.33) | CYP1A2ALDH1A1CYP2A6TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6553924 | 0.76 | KDM4E (0.33) | CYP1A2ALDH1A1CYP2A6TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL7772017 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6554716 | 0.72 | — | — | |
| SCHEMBL12537716 | 0.72 | ALDH1A1 (0.41) | CYP1A2CYP2C19ALDH1A1CYP2A6TSHR | |
| Hydrochloric Acid SCHEMBL29710442 | 0.72 | CYP1A2 (0.33) | CYP1A2CYP2C19ALDH1A1CYP2A6TSHR | |
| Hydrochloric Acid SCHEMBL7644367 | 0.71 | KDM1A (0.33) | ALDH1A1KDM4EMEN1MAPTHTT | |
| Hydrochloric Acid SCHEMBL7641960 | 0.71 | KDM1A (0.30) | — | |
| Hydrochloric Acid SCHEMBL2356550 | 0.70 | ALDH1A1 (0.39) | CYP1A2CYP2C19ALDH1A1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-1270602-B1 | CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER | IDEMITSU KOSAN CO (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-7176266-B2 | Catalyst for vinyl compound polymerization and process for producing vinyl polymer | IDEMITSU KOSAN CO. LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-6897261-B1 | Branched olefinic macromonomer, olefin graft copolymer, and olefin resin composition | IDEMITSU KOSAN CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |
| US-6835788-B2 | As polymerization catalyst | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20040259720-A1 | Catalyst for vinyl compound polymerization and process for producing vinyl polymer | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| US-20040097366-A1 | Polyolefin-based composite resin, method for production thereof, catalyst for polymerization of vinly compound and method for polymerization of vinly compound using the same | IDEMITSU KOSAN CO. LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| US-20030027716-A1 | Catalyst for vinyl compounds and process for production of vinyl polymers | IDEMITSU KOSAN CO. LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1270602-A1 | CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1209173-A1 | BRANCHED OLEFINIC MACROMONOMER, OLEFIN GRAFT COPOLYMER, AND OLEFIN RESIN COMPOSITION | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-05-29 | — | — | EP | disclosed |