Hydrochloric Acid

Hydrochloric Acid

SCHEMBL965025

C[Si](C)=[Zr+2]([C@@H]1C=Cc2c1ccc1ccccc21)[C@H]1C=Cc2c1ccc1ccccc21.[Cl-].[Cl-]

nearest known ligand 0.33

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Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.33
KDM1A O60341 1/20 0.33
ALDH1A1 P00352 3/20 0.32
CYP2A6 P11509 3/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC6A4 P31645 2/20 0.31
HPRT1 P00492 1/20 0.31
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6553924 1.00 KDM4E (0.33) KDM4EKDM1AALDH1A1CYP2A6TSHR
Hydrochloric Acid SCHEMBL7644367 0.86 KDM1A (0.33) KDM4EKDM1AALDH1A1SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL7641960 0.82 KDM1A (0.30) KDM1A
Hydrochloric Acid SCHEMBL5177193 0.79 ALDH1A1 (0.34) KDM4EALDH1A1CYP2A6TSHRHSD17B10
Hydrochloric Acid SCHEMBL15863693 0.77
Hydrochloric Acid SCHEMBL2779498 0.76
Hydrochloric Acid SCHEMBL5604216 0.76 CYP1A2 (0.34) KDM4EALDH1A1CYP2A6TSHRHSD17B10
Hydrochloric Acid SCHEMBL394837 0.76 KDM4E (0.33) KDM4EKDM1AALDH1A1CYP2A6TSHR
Hydrochloric Acid SCHEMBL627680 0.75 CHRNB2 (0.31)
Hydrochloric Acid SCHEMBL968018 0.73 KDM4E (0.33) KDM4EKDM1AALDH1A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299195-B2 Ethylene homopolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-8258247-B2 Catalyst component for polymerization of ethylene and process for producing ethylene polymer (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-04 US disclosed
US-20110003950-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-06 US disclosed
US-20100324243-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US disclosed
US-20100311934-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-09 US disclosed