Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593656 | 0.87 | KMT2A (0.36) | CYP1A2RETMAPTMEN1KMT2A | |
| SCHEMBL1026761 | 0.84 | KMT2A (0.36) | CYP1A2RETMAPTMEN1KMT2A | |
| SCHEMBL5604700 | 0.84 | ALDH1A1 (0.40) | CYP1A2POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL31133410 | 0.81 | DGAT2 (0.35) | DGAT2RETPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL5605093 | 0.81 | ALDH1A1 (0.43) | CYP1A2MAPTKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28686145 | 0.80 | SIRT2 (0.40) | CYP1A2HPGDPOLBMAPTMEN1 | |
| SCHEMBL29643977 | 0.80 | SIRT2 (0.40) | CYP1A2HPGDPOLBMAPTMEN1 | |
| SCHEMBL31475214 | 0.80 | CYP1A2 (0.39) | CYP1A2HPGDDGAT2POLBMAPT | |
| SCHEMBL4048725 | 0.80 | CYP1A2 (0.39) | CYP1A2HPGDDGAT2POLBMAPT | |
| SCHEMBL29233750 | 0.77 | ATR (0.36) | DGAT2RETPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |