Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.59 |
| ▸ | CTSL | P07711 | 8/20 | 0.59 |
| ▸ | CTSK | P43235 | 8/20 | 0.59 |
| ▸ | CTSB | P07858 | 5/20 | 0.59 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504861 | 0.87 | CTSS (0.60) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL3621514 | 0.87 | CTSS (0.60) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5606178 | 0.86 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5606039 | 0.81 | CTSL (0.39) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3618168 | 0.81 | CTSS (0.66) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5604851 | 0.79 | CTSK (0.39) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5522068 | 0.79 | CTSK (0.68) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5527516 | 0.75 | CTSS (0.72) | CTSSCTSLCTSKCTSBCTSV | |
| SCHEMBL5525339 | 0.74 | CTSL (1.00) | CTSSCTSLCTSKCTSBUSP30 | |
| SCHEMBL6867271 | 0.74 | CTSL (1.00) | CTSSCTSLCTSKCTSBUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | disclosed |