Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.52 |
| ▸ | CTSL | P07711 | 19/20 | 0.52 |
| ▸ | CTSK | P43235 | 14/20 | 0.45 |
| ▸ | CTSB | P07858 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604849 | 0.86 | CTSS (0.59) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3610313 | 0.82 | CTSL (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5606180 | 0.80 | CTSS (0.39) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5605465 | 0.78 | CTSL (0.42) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3619733 | 0.77 | CTSL (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3620955 | 0.76 | CTSL (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL13504861 | 0.73 | CTSS (0.60) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3621514 | 0.73 | CTSS (0.60) | CTSSCTSLCTSKCTSB | |
| SCHEMBL5606039 | 0.72 | CTSL (0.39) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3625025 | 0.71 | LTA4H (0.43) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | disclosed |