SCHEMBL5604938

SCHEMBL5604938

Nc1c(S)c2cccc3c(N)c(S)c4cccc1c4c32

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HPGD P15428 5/20 0.39
HSD17B10 Q99714 4/20 0.39
TSHR P16473 3/20 0.39
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
HKDC1 Q2TB90 1/20 0.36
KEAP1 Q14145 2/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
NFE2L2 Q16236 1/20 0.33
KDM4E B2RXH2 4/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
GLA P06280 2/20 0.32
ACHE P22303 2/20 0.32
CASP1 P29466 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605048 1.00 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL5605522 0.80 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL11847555 0.76 KDM4E (0.39) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL5605700 0.68 PKM (0.40) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL5939928 0.68 PKM (0.40) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL22931383 0.67 KDM4E (0.46) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL29553771 0.65 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL20735488 0.65 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL5605064 0.64 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10TSHRCYP3A4
SCHEMBL5605384 0.64 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed