Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621118 | 0.88 | CTSS (0.32) | CTSSCTSKKMT2AMAPTCTSL | |
| SCHEMBL3618558 | 0.84 | CTSS (0.34) | CTSSCTSKKMT2ACTSLLMNA | |
| SCHEMBL5605240 | 0.82 | CTSS (0.39) | CTSSCTSKCTSLCA12CA1 | |
| SCHEMBL3625350 | 0.76 | KMT2A (0.32) | CTSSCTSKKMT2AMAPTCTSL | |
| SCHEMBL8299221 | 0.73 | CTSS (0.40) | CTSSCTSKCTSL | |
| SCHEMBL3621114 | 0.73 | CTSS (0.40) | CTSSCTSKCTSL | |
| SCHEMBL3615924 | 0.72 | CTSS (0.40) | CTSSCTSKCTSL | |
| SCHEMBL6062764 | 0.71 | KMT2A (0.44) | CTSSCTSKKMT2A | |
| SCHEMBL3621944 | 0.71 | CTSS (0.33) | CTSSCTSKKMT2ACTSLLMNA | |
| SCHEMBL5604851 | 0.70 | CTSK (0.39) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | disclosed |