Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621118 | 0.85 | CTSS (0.32) | CTSSCTSKKMT2AALDH1A1CTSL | |
| SCHEMBL3619860 | 0.85 | CTSS (0.42) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5605243 | 0.84 | CTSS (0.31) | CTSSCTSKKMT2ACTSLLMNA | |
| SCHEMBL3621944 | 0.83 | CTSS (0.33) | CTSSCTSKKMT2AALDH1A1POLB | |
| SCHEMBL3618556 | 0.81 | CTSS (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL3618554 | 0.81 | CTSS (0.45) | CTSSCTSKCTSLCTSB | |
| SCHEMBL3613204 | 0.79 | FAAH (0.35) | CTSS | |
| SCHEMBL3621943 | 0.77 | CTSS (0.40) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6062764 | 0.73 | KMT2A (0.44) | CTSSCTSKKMT2AALDH1A1POLB | |
| SCHEMBL3625350 | 0.72 | KMT2A (0.32) | CTSSCTSKKMT2ACTSLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | CTSF, CTSB, CTSS | CTSS 3/4885CTSK 4/4885KMT2A 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.