Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594233 | 0.78 | KDM4E (0.44) | KDM4EHPGDRECQLKMT2AMEN1 | |
| SCHEMBL11640859 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL8230399 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL11792482 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL11792486 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL9674355 | 0.72 | DDB1 (0.41) | KDM4EALDH1A1KMT2A | |
| SCHEMBL8230121 | 0.70 | TRPA1 (0.41) | KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9584595 | 0.70 | ESR1 (0.43) | KDM4EALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL9584588 | 0.70 | ESR1 (0.43) | KDM4EALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL8911524 | 0.70 | HPGD (0.55) | KDM4EALDH1A1HPGDRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |