Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975941 | 0.88 | KDM4E (0.49) | KDM4EHPGDRECQLLMNAKMT2A | |
| SCHEMBL6398671 | 0.78 | HPGD (0.48) | KDM4EPDE4DHPGDRECQLLMNA | |
| SCHEMBL5605328 | 0.78 | KDM4E (0.56) | KDM4EPDE4DHPGDRECQLKMT2A | |
| SCHEMBL15358925 | 0.76 | IKBKB (0.40) | PDE4DHPGDIKBKBPRKAG1PRKAA1 | |
| SCHEMBL9790769 | 0.75 | PTGS2 (0.57) | KDM4EHPGDKMT2ACA1CA2 | |
| SCHEMBL29169546 | 0.75 | PTGS2 (0.57) | KDM4EHPGDKMT2ACA1CA2 | |
| SCHEMBL4595 | 0.75 | PTGS2 (0.57) | KDM4EHPGDKMT2ACA1CA2 | |
| SCHEMBL7338783 | 0.73 | PTGS2 (0.56) | KDM4EHPGDKMT2ACA1CA2 | |
| SCHEMBL225031 | 0.73 | PTGS2 (0.56) | KDM4EHPGDKMT2ACA1CA2 | |
| SCHEMBL6399683 | 0.73 | HPGD (0.46) | KDM4EPDE4DHPGDRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |