Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 5/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113878 | 0.81 | TTR (0.55) | TTRALDH1A1TRIM24HPGDALDH5A1 | |
| SCHEMBL10486972 | 0.81 | TTR (0.55) | TTRALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL28592447 | 0.79 | ALDH1A1 (0.54) | TTRALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL2110596 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TRIM24HPGDALDH5A1ABAT | |
| Syringaldehyde SCHEMBL30119623 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TRIM24HPGDALDH5A1ABAT | |
| Syringaldehyde SCHEMBL150376 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TRIM24HPGDALDH5A1ABAT | |
| Syringaldehyde SCHEMBL9328650 | 0.75 | PKM (0.59) | ALDH1A1TRIM24HPGDALDH5A1ABAT | |
| SCHEMBL2649406 | 0.75 | ERN1 (0.51) | TTRALDH1A1TRIM24HPGDALDH5A1 | |
| Syringaldehyde SCHEMBL31412823 | 0.74 | PKM (0.62) | ALDH1A1TRIM24HPGDALDH5A1ABAT | |
| SCHEMBL9761379 | 0.74 | TTR (0.51) | TTRALDH1A1TRIM24HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051314-A1 | CURCUMINOID COMPOUNDS FOR INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR-1 | AMERICAN DIAGNOSTICA INC. (US) | 2007-05-10 | — | — | WO | disclosed |