Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPP5C | P53041 | 2/20 | 0.50 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.50 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207070 | 1.00 | CTSB (0.57) | CTSBCTSSCTSKLMNAHTT | |
| SCHEMBL5605774 | 0.92 | PPP5C (0.53) | CTSBCTSSCTSKLMNAHTT | |
| SCHEMBL18485325 | 0.82 | HPGD (0.54) | CTSBCTSSCTSKLMNAHTT | |
| SCHEMBL14595387 | 0.81 | HSD11B1 (0.63) | CTSBCTSSCTSKALDH1A1KDM4E | |
| SCHEMBL699775 | 0.79 | HPGD (0.54) | CTSBCTSSCTSKTFPI2ALDH1A1 | |
| SCHEMBL16424491 | 0.78 | HPGD (0.52) | CTSBCTSSCTSKTFPI2ALDH1A1 | |
| SCHEMBL29012245 | 0.78 | CHRNB2 (0.55) | CTSBCTSSCTSKALDH1A1TSHR | |
| SCHEMBL5761060 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRADAM10ERBB2MMP2 | |
| SCHEMBL29012248 | 0.78 | CHRNB2 (0.55) | CTSBCTSSCTSKALDH1A1TSHR | |
| SCHEMBL18485318 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRADAM10ERBB2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166594-B2 | Antibacterial activity | AVENTIS PHARMA S.A. (FR) | 2007-01-23 | — | — | US | disclosed |