Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560587 | 1.00 | PTPN2 (0.53) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL498686 | 0.94 | PTPN2 (0.54) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560509 | 0.93 | PTPN2 (0.56) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560507 | 0.90 | PTPN2 (0.54) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560508 | 0.90 | PTPN2 (0.54) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560612 | 0.90 | PTPN2 (0.56) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560930 | 0.90 | ALDH1A1 (0.47) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560931 | 0.90 | ALDH1A1 (0.47) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL560866 | 0.86 | PTPN2 (0.58) | PTPN2PTPN1PTPRBACP1ALDH1A1 | |
| SCHEMBL561264 | 0.83 | PTPRB (0.53) | PTPN2PTPN1PTPRBACP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434737-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-09-06 | — | — | US | disclosed |
| US-8900830-B2 | Process for producing optically active succinimide derivatives | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2014-04-10 | — | — | US | disclosed |
| US-8633001-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130196388-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES | KYOWA HAKKO BIO CO., LTD. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2395097-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVE AND INTERMEDIATE THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, DHPS | PTPN2 3763/4885PTPN1 3929/4885PTPRB 2753/4885 |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, ALDH18A1 | PTPN2 3789/4885PTPN1 4075/4885PTPRB 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.