Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870487 | 0.91 | CYP3A4 (0.50) | KMT2AMEN1CYP3A4TSHRHPGD | |
| SCHEMBL6152948 | 0.86 | CYP3A4 (0.46) | KMT2AMEN1CYP3A4TSHRGAA | |
| SCHEMBL9717273 | 0.84 | ALDH1A1 (0.48) | CYP3A4TSHRGAAHPGDSMN1; SMN2 | |
| SCHEMBL10349842 | 0.83 | CYP3A4 (0.41) | KMT2AMEN1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL6152601 | 0.83 | ELANE (0.49) | CYP3A4TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL6151946 | 0.83 | ELANE (0.46) | KMT2AMEN1CYP3A4TSHRHPGD | |
| SCHEMBL9174753 | 0.83 | CYP3A4 (0.43) | KMT2AMEN1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL9700576 | 0.83 | CYP3A4 (0.43) | KMT2AMEN1CYP3A4TSHRGAA | |
| SCHEMBL6153149 | 0.83 | SNCA (0.51) | KMT2AMEN1CYP3A4TSHRGAA | |
| SCHEMBL1598844 | 0.83 | LMNA (0.48) | KMT2AMEN1CYP3A4TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | claimed |
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-20 | — | — | US | claimed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | disclosed |
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | AKR1C2, TECR, AKR1C4 | KMT2A 794/4885MEN1 3883/4885CYP3A4 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.