Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128327 | 0.73 | MAOA (0.58) | MAOAMAOBHTR2AHTR2CADRA2A | |
| SCHEMBL9124381 | 0.71 | AHR (0.50) | MAOAMAOBHTR2AHTR2CADRA2A | |
| SCHEMBL5605803 | 0.67 | MAOA (0.68) | MAOAMAOBHTR2AHTR2CADRA2A | |
| SCHEMBL7997285 | 0.65 | MAOA (0.43) | MAOAMAOBHTR2AHTR2CADRA2A | |
| Water SCHEMBL7564377 | 0.65 | MAOA (0.43) | MAOAMAOBHTR2AHTR2CADRA2A | |
| SCHEMBL28275733 | 0.64 | ALDH1A1 (0.45) | MAOAMAOBATMKMT2AMEN1 | |
| SCHEMBL8643737 | 0.64 | ALDH1A1 (0.42) | MAOAMAOBATMKMT2AMEN1 | |
| SCHEMBL5605804 | 0.64 | MAOA (0.50) | MAOAMAOBDRD2DRD1DRD3 | |
| SCHEMBL6659423 | 0.64 | MAOA (0.42) | MAOAMAOBHTR2AHTR2CADRA2A | |
| SCHEMBL11732034 | 0.64 | MAOA (0.68) | MAOAMAOBHTR2AHTR2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309733-B2 | Organopolysiloxane composition and electronic part encapsulated therewith | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-12-18 | — | — | US | disclosed |
| US-20050059772-A1 | Organopolysiloxane composition and electronic part encapsulated therewith | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-17 | — | — | US | disclosed |
| US-6838499-B2 | Comprising liquid base polymer, silicone elastomer powder, and crosslinking agent in putty form prior to curing; tack-free to the hand, easy to work, and adherent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-01-04 | — | — | US | disclosed |
| US-6812280-B2 | PREVENTS THE FILLER FROM SETTLING DOWN EVEN DURING LONG-TERM SHELF STORAGE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030195322-A1 | Organopolysiloxane compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-10-16 | — | — | US | disclosed |
| US-20030166739-A1 | Curable compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-09-04 | — | — | US | disclosed |
| US-5786414-A | CURABLE POLYSILOXANE | TOTO LTD. (JP) | 1998-07-28 | — | — | US | disclosed |