Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672300 | 0.87 | EPHX2 (0.37) | HPGDNPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5606541 | 0.77 | HDAC1 (0.40) | NPC1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3676253 | 0.72 | PKM (0.46) | HPGDHTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL3674836 | 0.70 | MRGPRX4 (0.41) | HPGDHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15197916 | 0.68 | MEP1B (0.48) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3677136 | 0.68 | MRGPRX4 (0.39) | HPGDNPC1HTTALDH1A1KDM4E | |
| SCHEMBL7640361 | 0.67 | SMN1; SMN2 (0.50) | HPGDNPC1HTTKMT2AMEN1 | |
| SCHEMBL3671198 | 0.66 | LMNA (0.37) | HTTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3672416 | 0.66 | MRGPRX4 (0.38) | HPGDNPC1HTTALDH1A1MAPT | |
| SCHEMBL12013627 | 0.65 | ACHE (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |