⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15300237 | 0.85 | CES1 (0.31) | — | |
| SCHEMBL2759733 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL561086 | 0.83 | OTUD7B (0.32) | — | |
| SCHEMBL2759734 | 0.81 | BACE1 (0.32) | — | |
| SCHEMBL2759735 | 0.80 | BACE1 (0.33) | — | |
| SCHEMBL2759726 | 0.80 | ADAM17 (0.32) | — | |
| SCHEMBL16588264 | 0.80 | ACACB (0.38) | — | |
| SCHEMBL2759736 | 0.80 | ACACB (0.38) | — | |
| SCHEMBL2759715 | 0.79 | PDE7A (0.33) | — | |
| SCHEMBL14998144 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421865-B1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-10 | — | — | EP | disclosed |
| EP-2421865-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | Syngenta Participations AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120035201-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| WO-2010115780-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-10-14 | — | — | WO | disclosed |