SCHEMBL561086

SCHEMBL561086

CON1CCC2(CC1)NC(=O)C(c1c(C)cc(C)cc1C)C2=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OTUD7B Q6GQQ9 3/20 0.32
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15300237 0.90 CES1 (0.31)
SCHEMBL2759726 0.89 ADAM17 (0.32) OTUD7B
SCHEMBL14998189 0.89 OTUD7B (0.30) OTUD7B
SCHEMBL14998190 0.89
SCHEMBL14998144 0.87
SCHEMBL2759716 0.86 CRBN (0.33)
SCHEMBL14998192 0.86
SCHEMBL2759733 0.85 ALDH1A1 (0.31)
SCHEMBL19139355 0.84 TACR1 (0.33) OTUD7BTACR1
SCHEMBL2759736 0.84 ACACB (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210037828-A1 TANK-MIX FORMULATIONS SYNGENTA PARTICIPATIONS AG (CH) 2021-02-11 US disclosed
US-10246459-B2 Use of tetramic acid derivatives as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2019-04-02 US disclosed
EP-2999333-B1 TANK-MIX FORMULATIONS SYNGENTA PARTICIPATIONS AG (CH) 2018-06-13 EP disclosed
US-9949476-B2 Tank-mix formulations SYNGENTA PARTICIPATIONS AG (CH) 2018-04-24 US disclosed
US-9949476-B2 Tank-mix formulations SYNGENTA PARTICIPATIONS AG (CH) 2018-04-24 US disclosed
US-20180030052-A1 USE OF TETRAMIC ACID DERIVATIVES AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-02-01 US disclosed
US-20180030052-A1 USE OF TETRAMIC ACID DERIVATIVES AS NEMATICIDES SYNGENTA PARTICIPATIONS AG (CH) 2018-02-01 US disclosed
US-9809593-B2 Use of tetramic acid derivatives as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2017-11-07 US disclosed
US-9809593-B2 Use of tetramic acid derivatives as nematicides SYNGENTA PARTICIPATIONS AG (CH) 2017-11-07 US disclosed
US-9485989-B2 Method of controlling neonicotinoid resistant hemiptera SYNGENTA PARTICIPATIONS AG (CH) 2016-11-08 US disclosed
US-8722578-B2 Spiroheterocyclic pyrrolidinedione herbicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2014-05-13 US disclosed
US-20140057930-A1 METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 US disclosed
US-20140057930-A1 METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 US disclosed
EP-2421865-B1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2013-07-10 EP disclosed
EP-2421865-A1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES Syngenta Participations AG (CH) 2012-02-29 EP disclosed
US-20120035201-A1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-02-09 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
WO-2010115780-A1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-10-14 WO disclosed
WO-2010052161-A2 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004105-A1 HERBICIDAL COMPOSITIONS DDT, CAT, HDHD5 OTUD7B 962/4885TACR1 894/4885
US-20120035201-A1 SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USED AS PESTICIDES DDT, PKD2, PKD1 OTUD7B 994/4885TACR1 181/4885
US-20180030052-A1 USE OF TETRAMIC ACID DERIVATIVES AS NEMATICIDES TBCA, TUBB, TUBA1C OTUD7B 2475/4885TACR1 811/4885
US-20210037828-A1 TANK-MIX FORMULATIONS CAT, TANK, FOXO3 OTUD7B 1790/4885TACR1 2485/4885
US-20140057930-A1 METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA DDT, NAMPT, NISCH OTUD7B 1849/4885TACR1 361/4885
US-10246459-B2 Use of tetramic acid derivatives as nematicides TBCA, TUBB, TUBA1C OTUD7B 2475/4885TACR1 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.