Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152422 | 0.83 | TSHR (0.37) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL10538421 | 0.82 | DNM1 (0.35) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL27224581 | 0.77 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL9875848 | 0.77 | ACE2 (0.42) | TSHRDNM1 | |
| SCHEMBL597280 | 0.74 | LMNA (0.41) | CTSKTSHRSMN1; SMN2DNM1 | |
| SCHEMBL27690882 | 0.74 | OPRM1 (0.41) | TSHRDNM1 | |
| SCHEMBL16649186 | 0.72 | TSHR (0.36) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL55980 | 0.72 | — | — | |
| SCHEMBL4764852 | 0.71 | DNM1 (0.33) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL1340398 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756271-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100587-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM 2,2-DISUBSTITUTED EPOXIDES | CSIR (ZA) | 2005-10-27 | — | — | WO | disclosed |