SCHEMBL5607468

SCHEMBL5607468

CC1Cc2cccc(-c3ccccc3)c2C1

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.55
HTR7 P34969 5/20 0.55
PRCP P42785 1/20 0.46
ANPEP P15144 2/20 0.43
IL1RN P18510 1/20 0.43
ERAP2 Q6P179 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27482804 0.98 HTR1A (0.54) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27444909 0.98 HTR1A (0.54) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27385758 0.95 HTR1A (0.51) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL11107496 0.83 HTR1A (0.50) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL29612355 0.81 BRD4 (0.45) HTR1AHTR7
SCHEMBL358604 0.79 HTR1A (0.50) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27520710 0.79 HTR7 (0.51) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27477925 0.79 HTR1A (0.50) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL16315939 0.78 PTGS1 (0.37) HTR1AHTR7
SCHEMBL11488158 0.78 PRCP (0.51) HTR1AHTR7PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101558089-B Solid catalyst for olefin polymerization, olefin polymerization method, and olefin polymer particles obtained by the polymerization method MITSU CHEMICALS INC 2012-09-19 CN disclosed
CN-101124252-B Metallocene catalysts, their synthesis and use in olefin polymerization NOVOLEN TECH HOLDINGS CV 2011-10-05 CN disclosed
CN-1946748-B Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV 2011-04-06 CN disclosed
CN-101558089-A Solid catalyst for olefin polymerization, olefin polymerization method, and olefin polymer particles obtained by the polymerization method MITSUI CHEMICALS INC (JP) 2009-10-14 CN disclosed
CN-101124252-A Metallocene catalysts, their synthesis and use in olefin polymerization NOVOLEN TECH HOLDINGS CV (NL) 2008-02-13 CN disclosed
EP-1866322-A2 PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-12-19 EP disclosed
CN-1946748-A Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV (NL) 2007-04-11 CN disclosed
WO-2006065844-A2 PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed
CN-1227271-C Solid catalytic composition for olefin polymerization ATOCHEM ELF SA (FR) 2005-11-16 CN disclosed
CN-1217891-C Method for preparing methylene radical bridged dicyclic pentylene compound HOECHST AG (DE) 2005-09-07 CN disclosed
CN-1200735-A Substituted indenyl contg. metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1998-12-02 CN disclosed
CN-1176955-A Preparation method of methylene bridged dicyclic pentadienyl compound HOECHST AG (DE) 1998-03-25 CN disclosed
CN-1160702-A Process for producing indene HOECHST AG (DE) 1997-10-01 CN disclosed
CN-1156728-A Olefin polymerization catalyst, process for preparing olefin polymer, and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1997-08-13 CN disclosed
CN-1148038-A Process for synthesizing carbon-bridged dicyclic pentylene compound HOECHST AG (DE) 1997-04-23 CN disclosed
CN-1109061-A Metallocenic compound HOECHST AG (DE) 1995-09-27 CN disclosed
CN-1107854-A Metalocenes compound HOECHST AG (DE) 1995-09-06 CN disclosed
EP-0213328-B1 DRY PESTICIDAL COMPOSITIONS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
US-4760084-A Aromatic hydrocarbon compound used as pesticide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-07-26 US disclosed
EP-0213328-A1 Dry pesticidal compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-03-11 EP disclosed