SCHEMBL358604

SCHEMBL358604

OC1Cc2cccc(-c3ccccc3)c2C1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 4/20 0.50
HTR7 P34969 4/20 0.50
PRCP P42785 1/20 0.45
ANPEP P15144 2/20 0.42
IL1RN P18510 1/20 0.42
ERAP2 Q6P179 1/20 0.42
ERAP1 Q9NZ08 1/20 0.42
TRPV1 Q8NER1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11107496 0.81 HTR1A (0.50) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL5607468 0.79 HTR1A (0.55) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27482804 0.78 HTR1A (0.54) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27444909 0.78 HTR1A (0.54) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL6999172 0.77 HTR1A (0.47) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27385758 0.75 HTR1A (0.51) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27520710 0.74 HTR7 (0.51) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL27477925 0.74 HTR1A (0.50) HTR1AHTR7PRCPANPEPIL1RN
SCHEMBL359381 0.73 HTR1A (0.55) HTR1AHTR7TRPV1
SCHEMBL27500103 0.73 HTR1A (0.49) HTR1AHTR7PRCPANPEPIL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102762532-B The manufacture method of cyano group alkenyl cyclopropanecarboxylic acid salt SUMITOMO CHEMICAL CO.,LTD. (JP) 2015-07-29 CN disclosed
EP-1792889-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2015-03-04 EP disclosed
CN-102365264-B Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL CO 2014-05-21 CN disclosed
EP-1547995-B1 Process for the preparation of carboxylic acid esters SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
EP-2418197-B1 PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2014-05-07 EP disclosed
US-8461370-B2 Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
EP-2537828-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT Sumitomo Chemical Company, Limited (JP) 2012-12-26 EP disclosed
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 US disclosed
CN-102762532-A Method for producing cyanoalkenylcyclopropanecarboxylic acid salt SUMITOMO CHEMICAL CO 2012-10-31 CN disclosed
CN-102365264-A Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL CO 2012-02-29 CN disclosed
US-4415748-A Intermediates for insecticidal synthetic pyrethroids FMC CORPORATION (US) 1983-11-15 US disclosed
EP-0085095-A1 INTERMEDIATES AND PROCESS FOR INSECTICIDAL SYNTHETIC PYRETHROIDS FMC Corporation (US) 1983-08-10 EP disclosed
EP-0069761-A4 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. FMC CORP (US) 1983-05-16 EP disclosed
WO-1983000485-A1 INTERMEDIATES AND PROCESS FOR INSECTICIDAL SYNTHETIC PYRETHROIDS FMC CORP (US) 1983-02-17 WO disclosed
EP-0069761-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. FMC CORP (US) 1983-01-19 EP disclosed
US-4346251-A 4-Substituted-2-indanols FMC CORPORATION (US) 1982-08-24 US disclosed
WO-1982002321-A1 (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES FMC CORP (US) 1982-07-22 WO disclosed
US-4335252-A A4-PHENYL-Z-INDANYL CYCLOPROPANE CARBOXYLATE FMC CORPORATION (US) 1982-06-15 US disclosed
US-4333950-A MITICIDES FMC CORPORATION (US) 1982-06-08 US disclosed
US-4263319-A CYCLOPROPYL ESTERS FMC CORPORATION (US) 1981-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120310003-A1 METHOD FOR PRODUCING CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID SALT MCCC2, AOC2, DDC HTR1A 1643/4885HTR7 1438/4885PRCP 678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.