Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 9/20 | 0.40 |
| ▸ | HTR7 | P34969 | 9/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607468 | 0.81 | HTR1A (0.55) | HTR1AHTR7 | |
| SCHEMBL27482804 | 0.80 | HTR1A (0.54) | HTR1AHTR7 | |
| SCHEMBL27444909 | 0.80 | HTR1A (0.54) | HTR1AHTR7 | |
| SCHEMBL27385758 | 0.77 | HTR1A (0.51) | HTR1AHTR7 | |
| SCHEMBL27816247 | 0.75 | PNMT (0.44) | BRD4CREBBPHTR7PARP1 | |
| SCHEMBL5952071 | 0.75 | ACHE (0.55) | BRD4CREBBPPARP1 | |
| SCHEMBL28465360 | 0.75 | CREBBP (0.43) | BRD4CREBBPPARP1 | |
| SCHEMBL5689519 | 0.73 | ACHE (0.49) | BRD4CREBBPHTR1AHTR7PARP1 | |
| SCHEMBL16316951 | 0.71 | CREBBP (0.40) | BRD4CREBBPPARP1 | |
| SCHEMBL5598185 | 0.71 | CREBBP (0.37) | BRD4CREBBPPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | disclosed |