Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219532 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28524737 | 0.75 | SMN1; SMN2 (0.36) | LMNAHSD11B1ALDH1A1EPHX2KMT2A | |
| SCHEMBL383263 | 0.75 | THRB (0.31) | CYP2C9 | |
| SCHEMBL819515 | 0.72 | LMNA (0.33) | LMNAALDH1A1EPHX2CYP3A4CYP2D6 | |
| SCHEMBL888634 | 0.72 | LMNA (0.39) | LMNAALDH1A1EPHX2CYP3A4CYP2D6 | |
| SCHEMBL5001838 | 0.71 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL11342798 | 0.71 | THRB (0.44) | LMNAHSD11B1ALDH1A1EPHX2CYP2D6 | |
| SCHEMBL2746956 | 0.70 | THRB (0.38) | HSD11B1ALDH1A1EPHX2CYP2C9 | |
| SCHEMBL888448 | 0.70 | EPHX2 (0.40) | LMNAALDH1A1EPHX2TSHR | |
| SCHEMBL888631 | 0.70 | EPHX2 (0.42) | LMNAALDH1A1EPHX2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |