SCHEMBL5608056

SCHEMBL5608056

COC(Cc1ccc(OCCN2c3ccccc3Cc3ccccc32)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.71
PPARA Q07869 16/20 0.60
PPARD Q03181 10/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531502 0.94 PPARG (0.81) PPARGPPARAPPARD
SCHEMBL7530774 0.92 PPARG (0.74) PPARGPPARAPPARD
SCHEMBL7533809 0.91 PPARG (0.63) PPARGPPARAPPARD
SCHEMBL7534341 0.88 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL7534721 0.86 PPARG (0.75) PPARGPPARAPPARD
SCHEMBL7529020 0.86 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL7532753 0.86 PPARG (0.80) PPARGPPARAPPARD
SCHEMBL7928584 0.85 PPARG (0.81) PPARGPPARAPPARD
SCHEMBL6754582 0.84 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL7536408 0.83 PPARG (0.69) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
EP-1687250-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS Takasago International Corporation (JP) 2006-08-09 EP disclosed
WO-2005051882-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142472-A1 Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids ALDH1A2, ALDH1A3, GRHPR PPARG 1052/4885PPARA 472/4885PPARD 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.