Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841938 | 1.00 | BLM (0.37) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL1903387 | 1.00 | BLM (0.37) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL7120217 | 0.98 | BLM (0.34) | BLMPMP22HSD17B10 | |
| SCHEMBL21070958 | 0.85 | MEN1 (0.37) | KDM4E | |
| SCHEMBL17183915 | 0.84 | BLM (0.34) | BLMPMP22HSD17B10 | |
| SCHEMBL21070941 | 0.84 | MEN1 (0.41) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL16353668 | 0.84 | KDM4E (0.42) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL18689524 | 0.84 | KDM4E (0.42) | BLMPMP22HSD17B10KDM4E | |
| SCHEMBL16353619 | 0.84 | MEN1 (0.41) | BLMPMP22HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL4699208 | 0.83 | HSD17B10 (0.36) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004815-B2 | Near-infrared quenching group | THE UNIVERSITY OF TOKYO (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20160296639-A1 | NEAR-INFRARED QUENCHING GROUP | THE UNIVERSITY OF TOKYO (JP) | 2016-10-13 | — | — | US | disclosed |
| EP-2419141-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | Koninklijke Philips Electronics N.V. (NL) | 2012-02-22 | — | — | EP | disclosed |
| EP-2419142-A2 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | Koninklijke Philips Electronics N.V. (NL) | 2012-02-22 | — | — | EP | disclosed |
| US-20120039803-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-02-16 | — | — | US | disclosed |
| US-20120034161-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034161-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KIT, PAICS, PROKR2 | BLM 2577/4885PMP22 3640/4885HSD17B10 1544/4885 |
| US-20120039803-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KIT, PROKR2, RET | BLM 2791/4885PMP22 4005/4885HSD17B10 2273/4885 |
| US-20160296639-A1 | NEAR-INFRARED QUENCHING GROUP | CRY2, RELA, CRY1 | BLM 259/4885PMP22 4499/4885HSD17B10 980/4885 |
| US-10004815-B2 | Near-infrared quenching group | CRY2, RELA, CRY1 | BLM 259/4885PMP22 4499/4885HSD17B10 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.