Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487087 | 0.84 | ACHE (0.56) | ALDH1A1SMN1; SMN2MAPTNPSR1AR | |
| SCHEMBL9487963 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTHPGDNPSR1 | |
| SCHEMBL16997341 | 0.80 | AR (0.41) | ARCYP3A4TSHRPTPN1SCN4A | |
| SCHEMBL6703974 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDARPTPN1HSP90AA1 | |
| SCHEMBL12585926 | 0.78 | PTPN1 (0.42) | ALDH1A1SMN1; SMN2MAPTARACHE | |
| SCHEMBL437049 | 0.77 | HSP90AA1 (0.50) | ALDH1A1SMN1; SMN2HPGDARACHE | |
| SCHEMBL9488114 | 0.77 | NPSR1 (0.51) | ALDH1A1SMN1; SMN2MAPTHPGDNPSR1 | |
| SCHEMBL13309714 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ARPTPN1FFAR1GAA | |
| SCHEMBL9487846 | 0.76 | LTA4H (0.52) | SMN1; SMN2MAPTARACHETSHR | |
| SCHEMBL16186449 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |