Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.34 |
| ▸ | GLMN | Q92990 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608925 | 0.92 | THRB (0.42) | NAAATHRBGLAALDH1A1DPP8 | |
| SCHEMBL5608031 | 0.90 | NPSR1 (0.39) | NAAATHRBGLAALDH1A1TSHR | |
| SCHEMBL5608429 | 0.85 | THRB (0.41) | NAAATHRBGLAALDH1A1DPP8 | |
| SCHEMBL1696580 | 0.83 | DPP4 (0.41) | NAAATHRBGLAALDH1A1TSHR | |
| SCHEMBL18469162 | 0.83 | DPP4 (0.41) | NAAATHRBGLAALDH1A1TSHR | |
| SCHEMBL24107384 | 0.82 | NPSR1 (0.34) | NAAATHRBGLAALDH1A1TSHR | |
| SCHEMBL5607937 | 0.82 | DPP8 (0.39) | NAAATHRBALDH1A1DPP8DPP9 | |
| SCHEMBL5608715 | 0.81 | THRB (0.42) | NAAATHRBGLAALDH1A1TSHR | |
| SCHEMBL5607984 | 0.81 | NAAA (0.37) | NAAATHRBGLAALDH1A1HSD17B10 | |
| SCHEMBL5607976 | 0.81 | NAAA (0.51) | NAAAGLAALDH1A1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |