SCHEMBL5607984

SCHEMBL5607984

CNC(=O)OC12CC3CC(OC(=O)NC)(C1)CC(OC(=O)NC)(C3)C2

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.37
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.32
GLA P06280 1/20 0.32
CA2 P00918 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608184 0.91 NAAA (0.33) NAAA
SCHEMBL5608925 0.88 THRB (0.42) NAAATHRBALDH1A1HSD17B10GLA
SCHEMBL5608713 0.88 THRB (0.34) NAAATHRBALDH1A1GLA
SCHEMBL5608427 0.87 NAAA (0.33) NAAA
SCHEMBL9925222 0.84 DPP8 (0.33) NAAA
SCHEMBL5607976 0.83 NAAA (0.51) NAAAALDH1A1HSD17B10GLACA2
SCHEMBL5608429 0.82 THRB (0.41) NAAATHRBALDH1A1HSD17B10GLA
SCHEMBL5608327 0.81 NAAA (0.38) NAAATHRBALDH1A1HSD17B10GLA
SCHEMBL5607937 0.78 DPP8 (0.39) NAAATHRBALDH1A1
SCHEMBL9925211 0.77 DPP8 (0.39) NAAATHRBALDH1A1HSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39744-E1 Adamantane derivatives and process for producing them DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-24 US disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed