Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608925 | 0.88 | THRB (0.42) | NAAAALDH1A1CA2HSD17B10GLA | |
| SCHEMBL5607984 | 0.83 | NAAA (0.37) | NAAAALDH1A1CA2HSD17B10GLA | |
| SCHEMBL5607937 | 0.82 | DPP8 (0.39) | NAAAALDH1A1 | |
| SCHEMBL5608429 | 0.82 | THRB (0.41) | NAAAALDH1A1CA2HSD17B10GLA | |
| SCHEMBL5608327 | 0.81 | NAAA (0.38) | NAAAALDH1A1HSD17B10GLANPSR1 | |
| SCHEMBL5608146 | 0.81 | POLB (0.41) | NAAAALDH1A1CA2LMNAGRIN2D | |
| SCHEMBL5607434 | 0.79 | ALDH1A1 (0.46) | NAAAALDH1A1GLANPSR1LMNA | |
| SCHEMBL28165311 | 0.79 | NAAA (0.47) | NAAAALDH1A1CA2GLANPSR1 | |
| SCHEMBL27928462 | 0.79 | ALDH1A1 (0.60) | NAAAALDH1A1CA2NPSR1CYP19A1 | |
| SCHEMBL5608715 | 0.78 | THRB (0.42) | NAAAALDH1A1CA2GLANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |