SCHEMBL5608713

SCHEMBL5608713

CNC(=O)OC12CC3CC(OC(=O)NC)(C1)CC(C(=O)O)(C3)C2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GLA P06280 1/20 0.33
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607984 0.88 NAAA (0.37) THRBALDH1A1GLANAAA
SCHEMBL5607434 0.86 ALDH1A1 (0.46) THRBALDH1A1GLANAAA
SCHEMBL5608698 0.82 ALDH1A1 (0.38) ALDH1A1GLA
SCHEMBL5607904 0.81 ALDH1A1 (0.36) THRBALDH1A1
SCHEMBL5608184 0.80 NAAA (0.33) NAAA
SCHEMBL5608925 0.78 THRB (0.42) THRBALDH1A1GLANAAA
SCHEMBL6561517 0.77
SCHEMBL5608427 0.77 NAAA (0.33) NAAA
SCHEMBL6561521 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5608715 0.75 THRB (0.42) THRBALDH1A1GLANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39744-E1 Adamantane derivatives and process for producing them DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-24 US disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed