Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460354 | 0.80 | RAB9A (0.36) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL814162 | 0.78 | MAPT (0.38) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL814420 | 0.77 | ADORA3 (0.34) | ADORA3ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL813809 | 0.76 | ADORA3 (0.35) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL813926 | 0.76 | ADORA3 (0.36) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL813989 | 0.76 | NPC1 (0.34) | ADORA3ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL814521 | 0.75 | ALDH1A1 (0.33) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL814661 | 0.75 | MAPT (0.41) | RAB9ANPC1CNR2MEN1KMT2A | |
| SCHEMBL813984 | 0.74 | ADORA3 (0.36) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL814096 | 0.74 | ADORA3 (0.37) | ADORA3ADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603957-B1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | INEOS SALES UK LTD (GB) | 2015-10-28 | — | — | EP | disclosed |
| EP-1603957-B1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | INEOS SALES UK LTD (GB) | 2015-10-28 | — | — | EP | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-20060094588-A1 | Polymerisation and oligomerisation catalysts | BARCLAYS BANK PLC (GB) | 2006-05-04 | — | — | US | disclosed |
| EP-1603957-A1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | Innovene Europe Limited (GB) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004083263-A1 | POLYMERISATION AND OLIGOMERISATION CATALYSTS | INNOVENE EUROPE LIMITED (GB) | 2004-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094588-A1 | Polymerisation and oligomerisation catalysts | CCNA1, AP2M1, AP2A1 | ADORA3 946/4885ADORA2A 596/4885ADORA1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.