Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609879 | 0.86 | RIPK1 (0.53) | RIPK1TAAR1TRPA1AOC3HTR2A | |
| SCHEMBL16360942 | 0.86 | RIPK1 (0.53) | RIPK1TAAR1TRPA1AOC3HTR2A | |
| SCHEMBL6280516 | 0.85 | RIPK1 (0.67) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL1861354 | 0.85 | RIPK1 (0.52) | RIPK1TAAR1TRPA1AOC3HTR2A | |
| SCHEMBL5213988 | 0.82 | RIPK1 (0.64) | RIPK1TAAR1TRPA1AOC3 | |
| Lithium SCHEMBL30777534 | 0.82 | RIPK1 (0.64) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL23710142 | 0.80 | TAAR1 (0.58) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL14644971 | 0.80 | TAAR1 (0.58) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL901919 | 0.80 | TAAR1 (0.58) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL23047599 | 0.79 | RIPK1 (0.55) | RIPK1TAAR1TRPA1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037955-A4 | CORROSION INHIBITOR FOR ALKANOLAMINE UNITS | BETZDEARBORN INC (US) | 2002-11-05 | — | — | EP | claimed |
| EP-1037955-A1 | CORROSION INHIBITOR FOR ALKANOLAMINE UNITS | BetzDearborn Inc (US) | 2000-09-27 | — | — | EP | claimed |
| US-5985179-A | ALKANEMONOTHIOL AND ALKANEDITHIOL COMPOUNDS FOR INHIBITING THE CORROSION OF METALS IN BOTH THE ACID GAS RICH AND LEAN PORTIONS OF THE ACID GAS REMOVAL UNIT, AQUEOUS ALKANOLAMINE SOLUTION | BETZDEARBORN, INC. (US) | 1999-11-16 | — | — | US | claimed |
| WO-1999010448-A1 | CORROSION INHIBITOR FOR ALKANOLAMINE UNITS | BETZDEARBORN INC. (US) | 1999-03-04 | — | — | WO | claimed |
| US-5843299-A | Corrosion inhibitor for alkanolamine units | BETZDEARBORN INC. (US) | 1998-12-01 | — | — | US | claimed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |
| US-6737544-B1 | HEATING ABOVE MELTING POINT | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-18 | — | — | US | disclosed |
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| CN-1189824-A | 1-amino-3-benzyluracils | BASF AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0542117-B1 | Process for the preparation of aryle esters of chloroformic acid | BASF AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| US-5274164-A | Preparation of aryl chloroformates | BASF AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0542117-A1 | Process for the preparation of aryle esters of chloroformic acid | BASF Aktiengesellschaft (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0542132-A1 | Process for the preparation of aryle esters of chloroformic acid | BASF Aktiengesellschaft (DE) | 1993-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | RIPK1 731/4885TAAR1 3666/4885TRPA1 3169/4885 |
| US-20040097728-A1 | Method for producing anellated tetrahydro-{1h}-triazoles | CBR1, CBR3, QSOX1 | RIPK1 2345/4885TAAR1 1548/4885TRPA1 1681/4885 |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | RIPK1 731/4885TAAR1 3666/4885TRPA1 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.