Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31085127 | 0.84 | RXRA (0.43) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL703244 | 0.84 | KIF11 (0.46) | UGT2B7AKR1C3AKR1C2PDE2A | |
| SCHEMBL17025358 | 0.84 | UGT2B7 (0.41) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL31085167 | 0.84 | UGT2B7 (0.41) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL3309320 | 0.84 | RXRA (0.43) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL31003210 | 0.84 | PDE2A (0.44) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL18291820 | 0.84 | PDE2A (0.44) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A | |
| SCHEMBL28059560 | 0.84 | TDP1 (0.43) | UGT2B7AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL13304198 | 0.83 | LMNA (0.40) | AKR1C3AKR1C2PTPN5CYP2C9 | |
| SCHEMBL18282695 | 0.82 | UGT2B7 (0.40) | UGT2B7AKR1C3AKR1C2PTPN5PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070196904-A1 | Method for the production of chiral secondary alcohols | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2007-08-23 | — | — | US | disclosed |
| EP-1725674-A1 | METHOD FOR THE PRODUCTION OF CHIRAL, SECONDARY ALCOHOLS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005095628-A1 | METHOD FOR THE PRODUCTION OF CHIRAL, SECONDARY ALCOHOLS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-10-13 | — | — | WO | disclosed |