Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15948147 | 0.82 | CHRNB2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5609416 | 0.82 | CACNA1G (0.33) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL5089860 | 0.81 | GPR3 (0.32) | GPR3 | |
| Hydrochloric Acid SCHEMBL2861269 | 0.78 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3674615 | 0.78 | BCHE (0.30) | — | |
| Hydrochloric Acid SCHEMBL16424309 | 0.76 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6906078 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL617245 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL16424157 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL16424505 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238026-B2 | PIGMENT CONCENTRATES AND METHODS FOR PRODUCTION THEREOF | BASF AG (DE) | 2007-01-24 | — | — | EP | claimed |
| US-6812274-B2 | Pigment concentrates and their production | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-02 | — | — | US | disclosed |
| US-20030019400-A1 | Pigment concentrates and method for production thereof | BASF AKTIENGESELLSHCAFT (DE) | 2003-01-30 | — | — | US | disclosed |