SCHEMBL68271

SCHEMBL68271

COc1c(O)ccc(O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
CA1 P00915 3/20 0.42
CA12 O43570 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
CYP3A4 P08684 2/20 0.42
CA2 P00918 2/20 0.42
MAOA P21397 2/20 0.42
SCN5A Q14524 1/20 0.41
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
MAOB P27338 1/20 0.39
TRPA1 O75762 1/20 0.39
ATM Q13315 1/20 0.39
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10460608 0.85 MAOA (0.43) TDP1CA1CA12CA7CA9
SCHEMBL768018 0.85 SCN5A (0.52) TDP1CA1CA12CA7CA9
SCHEMBL5141870 0.83 MAOB (0.45) TDP1CA1CYP3A4CA2ESR1
SCHEMBL29421917 0.83 MAOB (0.45) TDP1CA1CYP3A4CA2ESR1
SCHEMBL69925 0.83 TDP1 (0.52) TDP1CA1CA12CA7CA9
SCHEMBL29403778 0.83 TDP1 (0.52) TDP1CA1CA12CA7CA9
SCHEMBL12663229 0.81 TPMT (0.39) TDP1CA1CA12CA7CA9
SCHEMBL854840 0.81 ALDH1A1 (0.44) TDP1CA1CA12CA7CA9
SCHEMBL14539258 0.78 PDCD1 (0.39) TDP1CA1CA12CA7CA9
SCHEMBL19463402 0.78 TRPV1 (0.41) TDP1CA1CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12247130-B2 Laminatable ink AKZENTA PANEELE + PROFILE GMBH (DE) 2025-03-11 US disclosed
US-20230185197-A1 A COMPOSITION DATALASE LTD. (GB) 2023-06-15 US disclosed
EP-4143033-A1 A COMPOSITION DataLase Ltd (GB) 2023-03-08 EP disclosed
WO-2021219781-A1 A COMPOSITION DATALASE LTD. (GB) 2021-11-04 WO disclosed
US-20210253883-A1 LAMINATABLE INK AKZENTA PANEELE + PROFILE GMBH (DE) 2021-08-19 US disclosed
CN-112703231-A Laminable inks 阿卡曾塔板材型材有限公司 2021-04-23 CN disclosed
US-9522930-B2 Chartreusin analogues LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE (DE) 2016-12-20 US disclosed
US-20150197539-A1 NOVEL CHARTREUSIN ANALOGUES LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE (DE) 2015-07-16 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-20040242818-A1 Deodorizing agent for sulfur-or nitrogen-containing initiators UCB, S.A. (BE) 2004-12-02 US disclosed
US-20030152862-A1 Deodorizing agent for sulfur- or nitrogen-containing initiators UCB, S. A. (BE) 2003-08-14 US disclosed
US-6420001-B1 POLYMERIZED MESOGENIC MATERIAL WITH HELICALLY TWISTED STRUCTURE AND VARYING HELICAL PITCH; REFLECTIVE BROADBAND OR NOTCH POLARIZER OR AS A MULTICOLOURED FILM OR IMAGE IN LIQUID CRYSTAL DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2002-07-16 US disclosed
US-20020045676-A1 Polymerized mesogenic material with helically twisted structure and varying helical pitch; reflective broadband or notch polarizer or as a multicoloured film or image in liquid crystal displays COATES DAVID (GB) 2002-04-18 US disclosed
US-6319963-B1 Reflective film MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-11-20 US disclosed
EP-0982605-A1 Reflective film MERCK PATENT GmbH (DE) 2000-03-01 EP disclosed
EP-0292729-A2 Process for solid phase peptide synthesis BACHEM AG (CH) 1988-11-30 EP disclosed
EP-0065720-B1 PROCESS FOR PREPARING HYDROXYPHENYL AMINE DERIVATIVES CASSELLA Aktiengesellschaft (DE) 1985-01-09 EP disclosed
EP-0065720-A1 Process for preparing hydroxyphenyl amine derivatives CASSELLA Aktiengesellschaft (DE) 1982-12-01 EP disclosed
US-3970640-A Process for the production of polyphenylene ethers having a desired polymerization degree MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150197539-A1 NOVEL CHARTREUSIN ANALOGUES CYP17A1, CYP27A1, CYP46A1 TDP1 4308/4885CA1 4658/4885CA12 2756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.