Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947235 | 0.80 | GAA (0.39) | GAASMN1; SMN2MMP8MAPTCYP2C19 | |
| SCHEMBL5360149 | 0.76 | KDM4E (0.35) | ALDH1A1DGAT1 | |
| SCHEMBL12952357 | 0.74 | ALDH1A1 (0.38) | GAAMAPTCYP2C19ALDH1A1TDP1 | |
| SCHEMBL16370091 | 0.73 | MMP8 (0.36) | MMP8CYP2C19ALDH1A1TDP1 | |
| SCHEMBL234361 | 0.73 | MMP8 (0.41) | GAASMN1; SMN2MMP8CYP2C19ALDH1A1 | |
| SCHEMBL12927027 | 0.72 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL1812866 | 0.72 | TSHR (0.39) | GAADGAT1 | |
| SCHEMBL13143419 | 0.72 | MMP8 (0.39) | MMP8 | |
| SCHEMBL13788287 | 0.71 | MMP8 (0.44) | GAASMN1; SMN2MMP8CYP2C19AR | |
| SCHEMBL15233863 | 0.71 | MMP8 (0.53) | GAASMN1; SMN2MMP8CYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033013-A1 | POROUS MEDICAL CATHETER AND METHODS OF MANUFACTURE | MEDTRONIC, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| US-20030105453-A1 | Expanded polytettrafluoroethylene material is readily formable as a tube, provides a pore size on the order of 5-25 microns and is highly flexible and highly viable for catheter irrigation application | MEDTRONIC, INC. | 2003-06-05 | — | — | US | claimed |
| US-7175734-B2 | Expanded polytettrafluoroethylene material is readily formable as a tube, provides a pore size on the order of 5-25 microns and is highly flexible and highly viable for catheter irrigation application | MEDTRONIC, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| US-20030105453-A1 | Expanded polytettrafluoroethylene material is readily formable as a tube, provides a pore size on the order of 5-25 microns and is highly flexible and highly viable for catheter irrigation application | MEDTRONIC, INC. | 2003-06-05 | — | — | US | disclosed |