Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.89 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL9220822 | 1.00 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Formaldehyde SCHEMBL29262817 | 0.97 | TSHR (0.84) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Ethylene SCHEMBL27803431 | 0.94 | TSHR (0.89) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30671620 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL3409457 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30307036 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30812783 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Benzene SCHEMBL9751882 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL597672 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL2509 | 0.94 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117413826-A | Nanometer emulsion preparation containing trifluoropyridinamine and preparation method thereof | 广东真格生物科技有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116605927-A | Preparation method of ruthenium dioxide self-assembled hollow sphere with micro-nano hierarchical structure | 湖南工业大学 | 2023-08-18 | — | — | CN | claimed |
| CN-115281188-B | Preparation method and application of suspending agent containing water-soluble herbicide | 浙江新安化工集团股份有限公司 | 2023-05-19 | — | — | CN | claimed |
| CN-115281188-A | Preparation method and application of suspending agent containing water-soluble herbicide | 浙江新安化工集团股份有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-113463413-A | Efficient environment-friendly high-temperature dyeing auxiliary and preparation method thereof | 江苏海云花新材料有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113461732-A | 3, 3-diaryl acrylate/amide compounds containing triaryl phosphonium salt and preparation method and application thereof | 中国农业大学 | 2021-10-01 | — | — | CN | claimed |
| CN-109694482-B | Modified emulsified asphalt, preparation method thereof and fog sealing layer material | 国家能源投资集团有限责任公司 | 2021-08-10 | — | — | CN | claimed |
| CN-109694583-B | Fog sealing layer curing material and preparation method and application thereof | 神华集团有限责任公司 | 2021-04-06 | — | — | CN | claimed |
| WO-2020034181-A9 | QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 中国农业大学 | 2020-08-13 | — | — | WO | claimed |
| WO-2020034181-A1 | QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 中国农业大学 | 2020-02-20 | — | — | WO | claimed |
| CN-1288220-C | High strong adhesive and method for preparing same | MO WANQUAN (CN) | 2006-12-06 | — | — | CN | claimed |
| CN-1654577-A | High strong adhesive and method for preparing same | MO WANQUAN (CN) | 2005-08-17 | — | — | CN | claimed |
| CN-1207238-C | High performance aerated concrete | WANG RONG (CN) | 2005-06-22 | — | — | CN | claimed |
| CN-1533996-A | High performance aerated concrete | 王 | 2004-10-06 | — | — | CN | claimed |
| US-6706276-B2 | Matrix-forming agent, a bioadhesive, a buffer, and water; for use in the vagina; forms a semisolid matrix on contact with semen and causes hardening of cervical mucus; for STD (sexually transmitted disease) prevention and contraception | RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER | 2004-03-16 | — | — | US | claimed |
| US-20040009223-A1 | COMPOSITIONS AND METHODS FOR TRAPPING AND INACTIVATING PATHOGENIC MICROBES AND SPERMATOZOA | RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER | 2004-01-15 | — | — | US | claimed |
| WO-2003059197-A2 | THE USE OF SULFONATED COMPOUNDS AS A BARRIER CONTRACEPTIVE | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-07-24 | — | — | WO | claimed |
| US-20030134803-A1 | Use of sulfonated compounds as a barrier contraceptive | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-17 | — | — | US | claimed |
| EP-1263411-A2 | COMPOSITIONS AND METHODS FOR TRAPPING AND INACTIVATING PATHOGENIC MICROBES AND SPERMATOZOA | RUSH-PRESBYTERIAN-ST.LUKE'S MEDICAL CENTRE (US) | 2002-12-11 | — | — | EP | claimed |
| WO-2001066084-A2 | COMPOSITIONS AND METHODS FOR TRAPPING AND INACTIVATING PATHOGENIC MICROBES AND SPERMATOZOA | RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER (US) | 2001-09-13 | — | — | WO | claimed |