Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560775 | 0.90 | PTPRB (0.42) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL560776 | 0.90 | PTPRB (0.42) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL561889 | 0.88 | HTT (0.44) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL561888 | 0.88 | HTT (0.44) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL561048 | 0.83 | PTPRB (0.45) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL15903847 | 0.80 | CYP1A2 (0.46) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL560931 | 0.78 | ALDH1A1 (0.47) | PTPRBMEN1ALDH1A1KMT2A | |
| SCHEMBL560930 | 0.78 | ALDH1A1 (0.47) | PTPRBMEN1ALDH1A1KMT2A | |
| SCHEMBL4662942 | 0.77 | PTPRB (0.45) | HTTCYP1A2CYP2C9CYP2C19PTPRB | |
| SCHEMBL560683 | 0.75 | ALDH1A1 (0.49) | PTPRBMEN1ALDH1A1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434737-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-09-06 | — | — | US | disclosed |
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2014-04-10 | — | — | US | disclosed |
| US-8633001-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2395097-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVE AND INTERMEDIATE THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, DHPS | HTT 644/4885CYP1A2 276/4885CYP2C9 685/4885 |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, ALDH18A1 | HTT 870/4885CYP1A2 222/4885CYP2C9 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.