Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162368 | 1.00 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL243496 | 1.00 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL5614525 | 1.00 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL162014 | 1.00 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL13585526 | 0.98 | GGT1 (0.50) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL4263059 | 0.90 | GGT1 (0.44) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL29054949 | 0.89 | GGT1 (0.43) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL2720103 | 0.89 | ARG1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL11192504 | 0.82 | NOS1 (0.33) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL8687592 | 0.80 | GGT1 (0.65) | GGT1ARG1ARG2NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747269-A2 | RECOMBINANT ENZYME WITH ALTERED FEEDBACK SENSITIVITY | Metabolic Explorer (FR) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108561-A2 | RECOMBINANT ENZYME WITH ALTERED FEEDBACK SENSITIVITY | METABOLIC EXPLORER (FR) | 2005-11-17 | — | — | WO | disclosed |