SCHEMBL5614714

SCHEMBL5614714

CCCCc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 6/20 0.66
▸ FFAR1 O14842 1/20 0.55
▸ PPARG P37231 1/20 0.50
▸ HSD11B1 P28845 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ PLAAT3 P53816 1/20 0.48
▸ PLAAT5 Q96KN8 1/20 0.48
▸ PLAAT2 Q9NWW9 1/20 0.48
▸ PLAAT4 Q9UL19 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667215 0.94 LTA4H (0.65) LTA4HFFAR1HSD11B1ALDH1A1HSD17B10
SCHEMBL4546800 0.92 LTA4H (0.62) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL16558294 0.92 LTA4H (0.62) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL15312061 0.92 LTA4H (0.62) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL12721515 0.92 LTA4H (0.62) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL12056748 0.92 LTA4H (0.62) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL145761 0.92 LTA4H (0.52) LTA4HALDH1A1HPGDHSD17B10
SCHEMBL2453789 0.91 LTA4H (0.61) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL10630392 0.91 LTA4H (0.61) LTA4HFFAR1ALDH1A1HSD17B10
SCHEMBL427538 0.88 LTA4H (0.59) LTA4HFFAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 — — WO claimed
CN-122055371-A Faster automated iterative C-C bond formation 伊利诺伊大学评议会 2026-05-15 — — CN disclosed
WO-2025042679-A1 FASTER AUTOMATED ITERATIVE C-C BOND FORMATION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-02-27 — — WO disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 — — EP disclosed
CN-111662314-B Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-10-26 — — CN disclosed
US-11090325-B2 Compositions for treating ebola virus infection REDHILL BIOPHARMA LTD. (IL) 2021-08-17 — — US disclosed
EP-2832761-B1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO (JP) 2020-11-18 — — EP disclosed
CN-106905367-B Electron transport material or electron injection material, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-17 — — CN disclosed
CN-111909189-A Polycyclic aromatic compound, multimer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-10 — — CN disclosed
CN-111892615-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-06 — — CN disclosed
CN-103270079-A HIGH-MOLECULAR COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL CO 2013-08-28 — — CN disclosed
WO-2013004190-A1 AMINO-PROPYLENE-GLYCOL DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 中国医学科学院药物研究所 (CN) 2013-01-10 — — WO disclosed
US-20120270741-A1 BIOMARKER DISCOVERY IN COMPLEX BIOLOGICAL FLUID USING BEAD OR PARTICLE BASED LIBRARIES AND DIAGNOSTIC KITS AND THERAPEUTICS OPKO PHARMACEUTICALS, LLC 2012-10-25 — — US disclosed
US-20120214798-A1 Novel Ethanediamone Hepcidine Antagonists VIFOR (INTERNATIONAL) AG (CH) 2012-08-23 — — US disclosed
US-20120095004-A1 Sphingosine Kinase Inhibitors APOGEE BIOTECHNOLOGY CORPORATION (US) 2012-04-19 — — US disclosed
EP-1354887-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2007-04-25 — — EP disclosed
EP-1097158-B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INST TECHNOLOGY (US) 2006-01-25 — — EP disclosed
EP-1354887-A1 Ligands for metals and improved metal-catalyzed processes based thereon Massachusetts Insitute of Technology (US) 2003-10-22 — — EP disclosed
EP-1097158-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 — — EP disclosed
WO-2000002887-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095004-A1 Sphingosine Kinase Inhibitors SPHK1, SPHK2, S1PR1 LTA4H 944/4885FFAR1 1162/4885PPARG 3791/4885
US-20120270741-A1 BIOMARKER DISCOVERY IN COMPLEX BIOLOGICAL FLUID USING BEAD OR PARTICLE BASED LIBRARIES AND DIAGNOSTIC KITS AND THERAPEUTICS PMP22, TNFSF11, SELPLG LTA4H 1767/4885FFAR1 1823/4885PPARG 4127/4885
US-20120214798-A1 Novel Ethanediamone Hepcidine Antagonists HAMP, SLC40A1, FTH1 LTA4H 137/4885FFAR1 1215/4885PPARG 1604/4885
US-11090325-B2 Compositions for treating ebola virus infection NEFM, EIF2AK2, IRF3 LTA4H 3461/4885FFAR1 3733/4885PPARG 3654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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