Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 5/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.50 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135332 | 0.87 | GSK3B (0.56) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.85 | GSK3B (0.54) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| SCHEMBL29032840 | 0.85 | GSK3B (0.54) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| SCHEMBL5616554 | 0.84 | GSK3B (0.52) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| Biphenyl SCHEMBL8484559 | 0.83 | GSK3B (0.79) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| Biphenyl SCHEMBL27584116 | 0.81 | GSK3B (0.48) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| Phthalimide SCHEMBL3984602 | 0.80 | GSK3B (0.94) | GSK3BCASP3CASP2CASP7CASP6 | |
| Biphenyl SCHEMBL20954045 | 0.79 | GSK3B (0.52) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| SCHEMBL9016868 | 0.78 | GSK3B (0.50) | GSK3BPTP4A3CASP3CASP2CASP7 | |
| SCHEMBL16754925 | 0.78 | GSK3B (0.62) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60008247-A | — | — | None | — | — | JP | disclosed |
| US-5892061-A | REACTING A MONO- OR POLYCARBOXYLIC ACID WITH A MONO- OR POLYAMIDE IN THE PRESENCE OF A HALOIMINIUM SALT AND BASE; CATALYST SELECTIVITY | MITSUI CHEMICALS, INC. (JP) | 1999-04-06 | — | — | US | disclosed |
| JP-S608247-A | PHTHALAMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | SHOWA DENKO KK | 1985-01-17 | — | — | JP | disclosed |