Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.59 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sufentanil SCHEMBL6057143 | 0.83 | OPRM1 (0.85) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL192322 | 0.83 | OPRM1 (0.85) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL41227 | 0.83 | OPRM1 (0.85) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Citric Acid SCHEMBL10841118 | 0.82 | OPRM1 (0.55) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Citric Acid SCHEMBL10841111 | 0.82 | OPRM1 (0.55) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Citric Acid SCHEMBL28501611 | 0.80 | OPRM1 (0.67) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Citric Acid SCHEMBL10971572 | 0.77 | OPRM1 (0.70) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL26728 | 0.74 | OPRM1 (1.00) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL27722103 | 0.74 | OPRM1 (1.00) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28432948 | 0.74 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296830-A1 | METHODS OF ADMINISTERING DRUGS IN AN IMPLANTABLE MULTI-CHAMBER PUMP | Jazz Pharmaceuticals, Inc. (US) | 2014-10-02 | — | — | US | disclosed |
| US-20070270353-A1 | Intrathecal administration of ziconotide, an Omega-conopeptide, and the anitoxidant methionine, and an analgesic selected from morphine, hydromorphone, fentanyl, sufentanil, and buprenorphine; ziconotide retains its potency and is physically and chemically compatible with the analgesic | ELLIS DAVID J | 2007-11-22 | — | — | US | disclosed |