Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667392 | 0.85 | KIF11 (0.44) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL28033810 | 0.84 | MAPT (0.47) | KIF11KMT2AMAPTHTTLMNA | |
| SCHEMBL6719649 | 0.78 | ALDH1A1 (0.43) | MAPTCHRM2CHRM1CHRM3RAB9A | |
| SCHEMBL20541470 | 0.77 | HTT (0.54) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL11247 | 0.76 | KMT2A (0.46) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL6264368 | 0.76 | SCN5A (0.62) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL2984162 | 0.76 | CHRM3 (0.56) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL10958323 | 0.75 | SCN5A (0.45) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL27696956 | 0.74 | KIF11 (0.40) | KIF11KMT2AMAPTSCN5ASCN9A | |
| SCHEMBL3083611 | 0.74 | KMT2A (0.43) | KIF11KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137000-A2 | COMBINATION CANCER CHEMOTHERAPY | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2007-11-29 | — | — | WO | claimed |