Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529359 | 0.84 | MAPT (0.48) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL5617129 | 0.84 | KIF11 (0.44) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL4334002 | 0.83 | HTT (0.38) | MAPTKMT2ACYP2C19HTTCYP2D6 | |
| SCHEMBL20293767 | 0.83 | MAPT (0.47) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL4795423 | 0.82 | GABRA1 (0.36) | MAPTKMT2ACYP2C19CYP2D6CYP1A2 | |
| Piperazine SCHEMBL10994605 | 0.81 | KMT2A (0.39) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL7507157 | 0.80 | MAPT (0.44) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL5365607 | 0.79 | MAPT (0.46) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL2283147 | 0.77 | MAPT (0.48) | MAPTKMT2ACYP2C19HIF1AHTT | |
| SCHEMBL28043959 | 0.77 | CYP1A2 (0.44) | MAPTKMT2ACYP2C19HIF1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981458-A | Inhibitors of histone demethylases | EPITHERAPEUTICS APS | 2015-10-14 | — | — | CN | disclosed |