Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618490 | 0.87 | MAPK10 (0.49) | HTTMAPK1LMNAGAAMAPK8 | |
| SCHEMBL5617848 | 0.86 | MAPK8 (0.49) | GAAMAPK8MAPK9MAPK10MKNK2 | |
| SCHEMBL5617651 | 0.86 | ALDH1A1 (0.45) | HTTLMNAGAAMKNK2MKNK1 | |
| SCHEMBL5427414 | 0.78 | NPSR1 (0.36) | HTTGAAMKNK2MKNK1NPSR1 | |
| SCHEMBL5617823 | 0.77 | SMN1; SMN2 (0.48) | HTTMAPK1GAANPSR1MEN1 | |
| SCHEMBL5618112 | 0.76 | NPSR1 (0.39) | HTTGAAMAPK8MAPK9MAPK10 | |
| SCHEMBL5618715 | 0.76 | ALDH1A1 (0.40) | HTTLMNAGAANPSR1MEN1 | |
| SCHEMBL5618437 | 0.75 | NPSR1 (0.39) | HTTGAANPSR1MEN1HPGD | |
| SCHEMBL5631964 | 0.74 | CDK4 (0.42) | GAAMAPK8MAPK9MAPK10MKNK2 | |
| SCHEMBL5618494 | 0.73 | MAPK10 (0.62) | MAPK8MAPK9MAPK10MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203134-A1 | Benzimidazole Acetonitriles | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203134-A1 | Benzimidazole Acetonitriles | PKD1, GPR119, CCNI | HTT 1763/4885MAPK1 2788/4885LMNA 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.